Dozens were killed in Israeli strikes across the Gaza Strip on Thursday, the territory’s health ministry said, as U.S.-backed attempts to push Israel and Hamas to agree to a new cease-fire remain deadlocked.

Dozens more were injured in the attacks, according to the ministry, which does not distinguish between civilians and combatants.

Israel has threatened a significant military escalation in the coming days unless Hamas lays down its arms and frees the remaining hostages it holds. But the Palestinian armed group has rejected Israel’s conditions, demanding an end to the war and a full Israeli withdrawal in exchange for releasing the captives.